An introduction to shortening the upstream process development time of protein drugs and accelerating the entry into clinical methods
“Connect Upstream helps you accelerate into the clinicâ€
We all want to know how to accelerate into the clinic, so let's take a look at how the “industry big cockroach†WuXi PharmaTech does?
The case study published by WuXi PharmaTech "Shortening Timelines for Upstream Bioprocessing of Protein-based Therapeutics" explains how they can transform upstream processes by replacing traditional shake flasks and benchtop bioreactors with automated small and micro bioreactors. The development time was shortened from 22 weeks to 16 weeks.
The automation of the development process allows WuXi PharmaTech to determine the cell culture process with fewer resources. Process data results show a high degree of comparability between the ambr ® 15 micro bioreactor and the 200 liter BIOSTAT STR ® disposable bioreactor.
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