The poor are not only under pressure, but the DNA quality is also deteriorating!
Release date: 2015-05-14
On May 11th, the British "Daily Mail" website published an article entitled "Scientists say the quality of the poor DNA is degrading" said that stress may leave a lasting and destructive mark on the genes of the urban poor. The article is based on a research paper published in the Proceedings of the National Academy of Sciences (PNAS) on May 3. The study claims that as a result of the hardships of growth, the quality of the DNA of the poor is deteriorating, that is, the telomeres of people living in a poor environment, the DNA sequences that usually shorten with age, are shorter than those with better living conditions. .
Douglas A. Granger of the Johns Hopkins School of Public Health and others studied the telomeres of the poor, middle-class black, white, and Mexican-born residents of Detroit.
What is telomere?
Telomeres are small pieces of DNA-protein complexes present at the ends of linear chromosomes of eukaryotic cells. Together with telomere-binding proteins, they constitute a special "hat" structure that maintains chromosome integrity and controls cell division cycles. Telomeres and centromeres and origin of replication are the three major elements of chromosome integrity and stability, and the human genome is contained within the chromosome.
In young people, telomeres are approximately 8,000 to 10,000 nucleotides in length. Telomeres are shortened with each cell division and with pressure. Previous studies have found that telomere length can reliably predict human life expectancy.
The study found that low-income residents of Detroit City, regardless of the race they belong to, have a telomere length that is lower than the national average. Within this population, there is a clear distinction between telomere length and ethnic affiliation and income levels; the shortest telomere belongs to poor whites, while the Detroit white residents at the lower middle class have the longest study in the study. Telomere length; black residents have roughly the same telomere length regardless of income level, while poor Mexican residents have longer telomere lengths than higher-income Mexican residents.
Arline Geronimus, a visiting scholar at the Stanford Center for Advanced Studies and Nobel laureate, said in an interview: "Life in a highly impoverished, ethnically isolated community has some consequences." Arline believes that The telomere length of the Mexican poor in this study was longer than that of non-poor Mexicans, probably because the pressure on the former's growing environment was smaller. She said: "They have a support system and a cultural orientation that does not dampen self-worth."
In interpreting the results of studies on telomere length in black populations, the authors said: "The isolation of poor and non-poor blacks in everyday life is not as obvious as in white society."
Other studies on poor telomere DNA quality in poor populations
In addition to the above studies, Princeton University and Pennsylvania State University conducted a similar study last year. Their study of 40 9-year-old black boys found that children born in a poor environment had shorter telomeres. A stressful living environment can affect the DNA of a 9-year-old child.
A study conducted by Stanford University in the United States investigated the impact of bad human life on its DNA and found that if life is under heavy pressure due to poverty, the telomeres that dominate the lifespan will be more susceptible to compression. The shorter the telomeres, the higher the likelihood of premature death.
Source: Bio-Exploration
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