Australian scientists announced on February 17 that they had used a "continuous cell nuclear transfer" technique to clone a cow called "Brandy". This is the first time scientists have used this technology to clone cows. The team members were from the Monash Medical School in Australia and the Australian Gene Company. The cloned calf was born before Christmas last year and is currently in good health. According to Vanessa Hall, head of the research group, "Continuous Nucleus Transfer" technology has previously been used to clone mice and pigs. This is the first time this technique has been used to clone cattle. The traditional method of cloning is to use electrical pulses to fuse the "donor cell" cell nuclei with the cell nuclei that have been removed from the cell nucleus. After being implanted into the surrogate mother's uterus, the traditional method has a very small chance of survival. "Continuous nuclear transfer" technology is different from previous methods. In addition to the steps of the traditional cloning method, before implanting the cloned embryo in the uterus, the scientists first fuse the nutritive material of a fresh fertilized egg with the cloned embryo. The researchers said that adding more nutrients to cloned embryos can promote DNA recombination and improve embryo survival. Hall said that there is evidence that the reason for the low survival rate of embryos in the traditional cloning method may be that the operation process affects the development of the placenta, and although the “continuous cell nuclear transfer†technology has many operating steps, it may solve the above problems and improve the embryo’s Survival rate.
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