Three major gene editing technologies: CRISPR technology is prone to off-target effects
Looking at the genetic editing technology market, its current status is very similar to the tape format war between the Betamax video recorder produced by Sony in the 1980s and the VHS video recorder from JVC. At the time, although most experts thought that Betamax recorders were more feature-rich, better performing and more durable, on the other hand, VHS recorders were more affordable and suitable for long-term viewing, so in this battle The final winner is JV's VHS recorder. Medical market analysis company Kalorama combed the gene editing technology and company, and the author compiled and organized it for you.
Gene editing technology is currently facing the dilemma of Sony and JVC. In the field of gene editing, accurate and effective gene editing techniques based on zinc finger endonuclease and TAL effect factor have appeared many years ago. However, after the emergence of the simple and low-cost CRISPR technology, it has really driven the development of the gene editing technology market, or the establishment of the gene editing technology market due to the emergence of CRISPR technology.
Genomic editing is the process of modifying a particular biological DNA by introducing a functional protein at a specific target in the genome. The word "edit" is not complete enough. It does summarize the whole process, but it may have missed some important steps. For example, once a functional protein is introduced into the genome, it becomes an organism of its own editing, and it can also stimulate the mechanism of repair of the cell, making the gene inactivated or introducing a new target gene at a specific target of the genome.
Gene editing technology has many commercial applications in many fields, such as human health therapy, new plant varieties, new animal varieties, animal models for scientific research, new compounds, and the development of energy sources. Examples of various genetic editing-based projects that are currently under development include HIV/AIDS treatment, development of herbicide-resistant canola plants, treatment of acute lymphoblastic leukemia, development of genetically engineered soybeans, and even genetics. Edited Bama pig and rodent models.
At present, many companies have shown interest in the genetic editing technology market. MilliporeSigma, Thermo Fisher Scientific, Dharmacon, GeneCopoeia, GenScript, Horizon Discovery Group, OriGene, Transposagen, and ToolGen are major players in the gene editing technology market.
The genetic editing market is increasing year by year (tools, reagents, services, supply) Unit: Amount / Million Dollars 2014 – 2016.
Medical market analysis company Kalorama estimates that gene editing tools, reagents, services, models and other related products in the gene editing technology market account for about $608 million in market share compared to 233 million in 2014. The dollar has grown, and with the development of new applications and new projects, it is expected to achieve rapid growth in the next five years.
The continued development of therapeutics and agricultural applications using genetic editing technology, as well as increased public and private investment in gene editing, will also drive this market forward. At present, a large number of public and private investors have shown great interest in the development of human health therapy using gene editing technology.
Companies such as Bayer, Biogen, Juno Therapeutics, Novartis, Pfizer and Regeneron Pharmaceuticals are involved in the development of therapeutic drugs using gene editing techniques through various investments and collaborations with small companies. In addition to the development of human therapy, gene editing technology has commercial applications in many other fields, many of which are just beginning to be explored.
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