The relationship between drinking and heart disease, tell you now - more than 30,000 people investigate the link between alcohol intake and disease risk

You must know the dangers of excessive drinking. However, for a long time, the argument that moderate drinking is good for health, especially cardiovascular health, has also been widely disseminated and accepted and accepted.

However, there is a serious lack of medical research evidence. With the exception of a few rigorous, small epidemiological studies supporting these claims, there has been no repeated verification and recognition of the accepted views by the medical community. The most appropriate for “moderate” and “excessive” depends on the individual.

Until recently, a study based on 35,132 people published in the open access journal BMC Medicine provided an important puzzle for this overall blueprint: a research team led by University College London and Cambridge University It was found that during the 10-year period, moderate but irregular drinkers, those who had used alcohol but had abstained from alcoholism, and those who never reported alcohol in self-reported patients suffered from coronary heart disease compared with those who followed the regular drinking guidelines in the UK. The risk is higher, but non-drinkers who follow this pattern are limited to women.

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Rumors or science?

In the relationship between drinking and disease, it has been claimed that medical research supports it to reduce the risk of cardiovascular disease.

As early as the early 1990s, the famous "Lancet" journal published a paper entitled "The French Paradox of Wine, Alcohol, Platelets, and Coronary Heart Disease." Based on epidemiological data, the French high-saturated fat diet is a typical Western diet, but their coronary heart disease mortality rate is far lower than other Western countries such as the United States and the United States. It is concluded that the wines that the French drink every day provide protection for the French. As for the mechanism, it is considered that wine can increase the concentration of high-density cholesterol (HDL) in blood, and on the other hand, it can prevent the aggregation of platelets, thereby preventing the formation and progression of atherosclerosis.

This paper once caused a huge wave of Western public opinion, because the media have begun to make great use of the benefits of so-called drinking.

But in 2015, the study conducted by the University of Gothenburg in Sweden concluded that the protective effect of moderate alcohol consumption on reducing the risk of coronary heart disease is only seen in lucky people with specific gene types. It is a bit “cruel” that this lucky person only accounts for 15% of the population.

"No law" is more dangerous

Now, the researchers' latest findings suggest that irregular drinking can increase the risk of cardiovascular disease, but the amount of alcohol recommended in the health guidelines may be protective against cardiovascular disease.

Dr. Dara O'Neill from University College London said: "Our research uses long-term tracking data to distinguish between people who never drink alcohol and those who have used alcohol but have abstained from alcohol. According to widely accepted theory, the latter suffers from the crown. The risk of heart disease should be higher than the former. We want to test whether this is the case. The final result confirms this conclusion, but we find that there is a gender difference in this theory. Women who never drink alcohol have a higher risk of coronary heart disease than regularity. Drinking people are high, but men who never drink alcohol do not have this phenomenon."

Overall, the 35,132 people were divided into 6 groups for study, and 1,718 (4.9%) had coronary heart disease during the study period, of which 325 (0.9%) were seriously ill. The incidence of coronary heart disease was the highest among those who had used alcohol but had abstained from alcohol, reaching 6.1%, of which 1.2% were serious cases; the lowest among regular heavy drinkers, 3.8%, of which 0.6% were serious cases. The researchers cautioned that because of the small number of heavy drinkers involved in the study, especially women who are heavily drinkers, there is considerable doubt about the incidence of coronary heart disease in heavy drinkers.

Dr. O'Neill said that in population-level studies, the number of samples of heavy drinkers is often insufficient, so although studies have shown that the incidence of coronary heart disease in heavy drinkers is not high, the interpretation of this result must be very cautious, after all, Knowing that heavy alcohol intake can cause many health problems.

The results of this study suggest that long-term and unstable drinking behavior may lead to coronary heart disease risk, which may be due to unstable drinking behavior, which often reflects more instability in lifestyle, including health status. Good or life pressure.

Different age risks

Many changes in lifestyle may also be related to differences in risk between different age groups observed by the investigator.

Dr. O'Neill said that after grouping the sample population by age, they found that the risk of coronary heart disease was increased in irregular and moderate drinkers. It only existed in people over 55 years old, and this phenomenon was not found in younger groups. The reason may be that older people experience lifestyle changes like retirement, and this type of change is often accompanied by an increase in alcohol consumption, all of which may cause risk differences between ages.

To investigate the relationship between coronary heart disease and long-term drinking behavior, the researchers analyzed prospective longitudinal data on self-reported weekly drinking in six groups, five of which were from the UK and one from In France, the data includes information on alcohol consumption and coronary heart disease over a decade.

Long-term drinking behavior is based on self-reported alcohol types; half-pints (about 240 ml) of beer or cider, small glasses of red wine and a glass of spirits are converted to 8 grams of alcohol in the UK study, while in French studies Converted to 10 grams of alcohol. The standard for moderate drinking is that men do not exceed 168 grams of alcohol per week, and women do not exceed 112 grams of alcohol per week.

The research team cautioned that non-drinkers in this study may also include people who have used alcohol but have abstained from alcohol because of lack of alcohol intake information prior to the 10-year study. Severe drinkers who are sick may or may not be included in the study sample because they are likely to withdraw from the project early in the study. In addition, the six studies included in this project are all observational studies, so it is impossible to make causal conclusions.

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