Arburg: Medical injection molding technology that dissolves itself after inhalation of implants

In medical applications, special inhalable implants, such as screws and pins, are used to secure bones and tissues. One advantage of an absorbable implant is that it can be removed without surgery after healing. ARBURG has developed new technologies in the high-end field of medical care to create inhalable implants for fixed bones and tissues.

Arburg and BIOVISION work together to process polylactic acid (PLA) on electric ALLROUNDERA, for example, into bone nails for medical technology. The polylactic acid (PLA)-based material has the advantage that it can be dissolved automatically in the human body within a prescribed time. However, due to the toughness of PLA, the requirements for processing PLA plastics are very demanding, and it is necessary to have corresponding professional skills in injection molding. Arburg has made new technical achievements in this respect.

15mm special screw solves tough problems

Sven Kitzlinger from Arburg Medical Technology Application Consulting said, “The cost of purchasing raw materials is very expensive, it costs thousands of euros per kilogram, and it is very sensitive to high temperatures and cannot stay in the barrel for a long time.” So, people are injecting No mistakes can be made in the process. Excessive material shear forces during plasticization can also damage the material, causing it to dissolve prematurely in the body.

Arburg: Successfully developed medical injection molding technology based on PLA

Arburg: self-dissolving after inhalable implants

“In order to be able to plasticize and reduce the residence time of the material in the barrel, we have used a special 15 mm screw with a widened spacer and a chromium nitride (CrN) coating. This makes it reliable. Avoid bad material degradation and avoid the amount of corrosion,” says Sven Kitzlinger.

ARBURG has decades of experience in medical technology and automation. Modular equipment and a one-stop turnkey solution, with the right partners, can be tailored to each customer with different needs.

At the 2016 Technical Festival, ARBURG demonstrated the use of an electric ALLROUNDER 370 A to process Evonik's "Resomer L210S". The clean room machine equipped with a stainless steel plate clamping unit meets the highest hygiene requirements of ISO 13485, while ISO 13485 is the FDA and GMP guidelines. An ISO7 grade fairing above the clamping unit ensures ionization, ensuring essential clean air during production. “Even if the injection weight is less than one gram, the use of our miniature injection molding module makes sense,” adds Sven Kitzlinger. “It can selectively combine a 18 or 15 mm screw for melting material with an 8 mm screw for injection.” This ensures a gentle processing of the plastic on a first-in, first-out basis and also makes up for simplicity. Insufficient injection of ground piston.

Follow-up or further research on personalization

Abbé works with it BIOVISION is very good at injection molding of absorbable plastics. Using an ALLROUNDER 270 A and micro-module, PLA and other materials can be processed together into a "PolyPIN" type 25- to 60-mm long nail that is used in surgery for fracture fixation and biomechanically reduced power. After about two years, the implant will dissolve.

In addition, Arburg showed another interesting application area on the technical day of 2016: a personalized additive made entirely in accordance with the patient's design. In principle, freeformer can be used to process medical PLA, such as a face bone and a skull. In this new field, Arburg will have further research.

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