Natural childbirth or more easily enhance the development of the neonatal immune system

Release date: 2014-07-15

Many studies have shown that babies born in caesarean section often have different gut flora compared to naturally born babies, but the cause of this phenomenon and its impact on the body's immune system is unclear; recently, from the University of Copenhagen The researchers studied newborn mice to reveal the effects of birth patterns on the development of the mouse's immune system. The relevant research results were published in the journal Journal of Immunology.

The researchers found that the number of cells that enhance the immune system in the pups of mice born by caesarean section is often small, and that pups born by natural delivery can be exposed to more bacteria than caesarean section, the researchers suggest A health hypothesis, that is, a baby born in a natural mode of birth, whose immune system can learn to distinguish between harmless molecules and foreign molecules.

Caesarean-born pups have a small amount of specific cells, and this cell plays an important role in inhibiting the response of reactive immune cells to their own molecules, diet, and harmless gut flora. Autoimmune diseases such as type I diabetes, Crohn's disease, and allergies are diseases caused by overreaction of the immune system.

The researchers then looked for signs of type 1 diabetes in the caesarean section of the caesarean section. The results were not found. The next step is to conduct an in-depth study to identify whether cubs born in caesarean section are more susceptible to other types of autoimmune diseases. And carry out further clinical research; research on mouse models provides some clues to reveal the molecular mechanisms of many human diseases, so in the long run, researchers need to develop methods to strengthen the development of the neonatal immune system. Prevent them from developing autoimmune diseases.

Source: Bio Valley

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