In the antibiotic bottle small-volume injection drug production line, the antibiotic glass bottle is a package material that is in direct contact with the powder or the liquid medicine, and the corresponding aseptic production process requires the bottle to be dried and depyrogenated. The tunnel type sterilization dryer is a device for sterilizing, drying and depyrogenating the antibiotic bottle. Usually, the dry heat sterilization method is adopted. The dry heat often has two types of parallel flow of hot air and far infrared heating.
The tunnel type sterilizer is an integral tunnel structure, which is divided into three parts: preheating section, high temperature sterilization section and cooling section. After sterilization, the particles of antibiotic glass bottles reach the level 100 cleanliness requirement, and the bacterial endotoxin drops greatly. Logarithmic units and microorganisms must not be detected.
According to different types, general tunnel sterilization dryers are divided into two types according to the heat sterilization mode. One is hot air circulation (that is, parallel flow of hot air), and the other is far infrared radiation. The common point is dry heat sterilization.
The far-infrared radiation type tunnel sterilizer is a domestic product with a long history. It is characterized by the dual effects of radiant heat and hot air laminar flow during sterilization and drying. The heat penetration is strong; the spare parts cost is relatively low. . However, the imperfection of the far-infrared radiation tunnel sterilizer is that it is greatly affected by the airflow interference in the box and the opening and closing of the electric heating tube, and has high requirements for the second-stage wind pressure control before and after the oven; It is decided that the length of the box is longer than that of the hot air circulation type; only the whole row of bottles can be pushed in, so that the temperature of the bottle is basically the same, so that the heat penetration index can be basically ensured.
In comparison, the hot air circulation tunnel type sterilization dryer is characterized by easy control of temperature and hot air pressure difference; temperature distribution is uniform; the whole box length is shorter than the far infrared radiation type. However, the imperfection is that the hot air circulation tunnel type sterilization and drying adopts a high-quality high-efficiency filter, and the use cost is relatively high, and the hot air circulation type preheating section heats up quickly, and the bottle wall is evenly distributed. Sex has certain requirements.
Wenzhou Kangpai Pharmaceutical Machinery Co., Ltd. technical personnel introduced that the second type of tunnel-type sterilization drying oven has its own characteristics, and the equipment on the market can basically meet the demand of pharmaceutical production.
It is understood that in the past, Chinese pharmaceutical companies generally selected domestic traditional classic far-infrared heat radiation type to sterilize and dry antibiotic bottles because of their lower price and lower operating costs. However, in recent years, with the large number of control bottles used in domestic antibiotic aseptic preparations, its thin wall and uniformity characteristics, combined with the control of hot air circulation type and the uniformity of heat, the hot air circulation type tunnel sterilization dryer It is widely used and is also receiving market attention.
It is reported that the tunnel sterilizing oven introduced by Jiangyin Yiyida Machinery Co., Ltd. is widely used in various ampoule bottles for pharmaceutical production, drying and sterilizing of easy-open bottles, vials and other glass containers, and also for chemical, food, and electronic products. Drying of materials in industrial sectors such as industry.
The author believes that China's pharmaceutical industry is currently in the development stage, while the demand for tunnel sterilization equipment is expanding, and its requirements are constantly improving. Equipment manufacturing enterprises should seize the user's requirements and suggestions, and at the same time expand the production scale, more humanized design, promote equipment further update and upgrade, so as to better serve the Chinese pharmaceutical industry.
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