good news! Diabetes does not need an injection
Release date: 2015-07-01
There are more than 387 million people with diabetes worldwide, and by 2035, the number of people with diabetes is expected to reach 592 million. Type 1 and type 2 diabetes patients have tried various methods to try to keep their blood sugar levels under control. They regularly take blood on their fingers or repeatedly inject insulin. This process is painful and inaccurate. In addition, injection of the wrong dose of insulin can lead to serious complications such as blindness, amputation, and even diabetic coma and death.
Fortunately, this painful insulin injection may become a history of insulin patients. Recently, researchers from the University of North Carolina invented a "smart insulin patch" that not only detects elevated blood sugar levels, but also allows the patch to be used when needed. A certain dose of insulin is secreted in the bloodstream. The study was recently published in the journal PNAS.
This patch is a very thin square, no more than a penny, covered with more than 100 tiny pins, each about the size of an eyelash. These microneedles contain insulin and glucose-sensing enzymes that release insulin when blood sugar levels rise.
The researchers tested the efficacy of this smart patch on a mouse type 1 diabetes model. At the same time, they injected insulin into another group of mice. The results showed that in mice injected with insulin, blood sugar levels can be reduced to the normal range, however, blood sugar levels will quickly return to the high blood sugar range. In contrast, mice in the smart patch group had their blood glucose levels lowered to normal levels within 30 minutes and lasted for several hours.
Researchers say the patch can become smarter in the future. For example, smart patches for more personalized treatments can be designed based on the weight of the diabetic patient and the sensitivity to insulin. However, more preclinical trials and human clinical trials are still needed before this smart patch enters the clinic and is used in diabetic patients. At present, this treatment method shows great prospects and hopes.
Source: Bio Valley
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